Using extreme cold to remove abnormal skin growths is a standard medical procedure that utilizes extreme cold to eliminate dysplastic tissue. The dominant method is liquid nitrogen treatment, which typically involves depositing cryogenic nitrogen to the lesion. This agent has a temperature of –196°C, which is sufficiently frigid to cryo-destroy the abnormal cells without causing significant harm to nearby dermal layers when applied with proper technique.

The biological principle lies in how skin cells react to extreme hypothermia. When the freezing agent is applied, intracellular ice form within cellular membranes, breaking down their internal structures. This trauma impedes the cells from functioning properly and eventually causes them to undergo necrosis. The body then naturally removes the necrotic cells over the subsequent weeks.

For warts, which are induced by the HPV, freezing destroys not only the clinical manifestation but also the subcutaneous viral reservoirs beneath the surface. For pigmented lesions, especially benign ones, freezing eliminates the melanocyte aggregates that form the mole.

Careful execution is vital when performing cryoablation. Medical professionals are certified to control the length and depth of the freeze to minimizing risk to healthy skin. Too much freezing can lead to fluid-filled lesions, permanent marks, or hyperpigmentation. That’s why it’s advisable to have the procedure done by a qualified medical professional rather than attempting over the counter home remedies, which may not be accurate and can lead to complications.

Patients often feel a transient burning sensation during the treatment, followed by mild discomfort afterward. A fluid-filled bubble may form, which is common and part of the healing process. Avoiding moisture helps prevent infection and accelerates recovery. It’s also important to not disturbing the treated area, as this can increase the risk of scarring or spreading the virus if it’s a wart.

Some lesions are appropriate for freezing. Moles that are irregular in shape, color, or size should be assessed by a specialist first, as they could be signs of skin cancer. In such cases, a biopsy may be required before any treatment. Similarly, warts on the face or genitals require tailored protocols due to the thin dermal structure in those areas.

Freezing treatment is well-tolerated, effective, and efficient, often taking only a few minutes per lesion. Multiple treatments may be necessary for stubborn warts, but nearly all see clearance after two treatments. When performed correctly by experienced providers, freezing warts and moles is a clinically validated and نیتروکسی پن non-surgical way to address common skin concerns.